Acute respiratory distress syndrome (ARDS) is the most severe form of acute lung injury, characterized by acute pulmonary infiltrates, abnormal respiratory system compliance, and moderate to severe hypoxemia. The etiology of ARDS is either direct (e.g., pneumonia) or indirect (e.g., sepsis) insult to the lungs by various inflammatory mediators. Jun 13, · Overview Acute respiratory distress syndrome (ARDS) occurs when fluid builds up in the tiny, elastic air sacs (alveoli) in your lungs. The fluid keeps your lungs from filling with enough air, which means less oxygen reaches your bloodstream. This deprives your organs of the oxygen they need to function.
◆ The pathophysiology of ARDS is complex and involves acute lung inflammation, increased permeability of the lung endothelial and epithelial barriers, inhibition of surfactant function, impairment of alveolar fluid clearance mechanisms and systemic inflammation. A 1-year survey of patients in three hospitals identified patients who had one predisposition and 57 who had several predispositions to the adult respiratory distress syndrome. From the total predisposed population of patients, 68 subsequently developed the syndrome. An additional 20 patient Cited by:
Pathophysiology of adult respiratory distress syndrome. Lamy ML, Fallat RJ, Koeniger EL, Dietrich HP, Kamm B, Hill JD. We have studied 45 patients with adult respiratory distress syndrome (ARDS). Pathological studies were performed on 30 Cited by: 7. Mar 23, · Acute respiratory distress syndrome (ARDS) is a severe lung condition. It occurs when fluid fills up the air sacs in your lungs. Too much fluid in your lungs can lower the amount of oxygen or.